Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ

Sikkeland LIB, Qiao SW, Ueland T, Myrdal O, Wyrożemski Ł, Aukrust P, Jahnsen FL, Sjåheim T, Kongerud J, Molberg Ø, Lund MB, Bækkevold ES (2021)
Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
Eur Respir J, 57 (3)
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An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics

Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT (2020). An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. Sci Transl Med, 12 (565). PubMed 33055243 DOI 10.1126/scitranslmed.abb0580

CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Sætre F, Hagen KT, Yaqub S, Øyen O, Horneland R, Aandahl EM, Aabakken L, Bækkevold ES, Jahnsen FL (2020). CD4+ T cells persist for years in the human small intestine and display a TH1 cytokine profile. Mucosal Immunol, 14 (2), 402-410. PubMed 32572129 DOI 10.1038/s41385-020-0315-5

Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease

Divito SJ, Aasebø AT, Matos TR, Hsieh PC, Collin M, Elco CP, O’Malley JT, Bækkevold ES, Reims H, Gedde-Dahl T, Hagerstrom M, Hilaire J, Lian JW, Milford EL, Pinkus GS, Ho VT, Soiffer RJ, Kim HT, Mihm MC, Ritz J, Guleria I, Cutler CS, Clark RA, Jahnsen FL, Kupper TS (2020). Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease. J Clin Invest, 130 (9), 4624-4636. PubMed 32516138 DOI 10.1172/JCI129965

Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020). Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial. PLoS One, 15 (5), e0232739. PubMed 32437393 DOI 10.1371/journal.pone.0232739

Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced

Seiron P, Wiberg A, Kuric E, Krogvold L, Jahnsen FL, Dahl-Jørgensen K, Skog O, Korsgren O (2019). Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced. J Pathol Clin Res, 5 (4), 248-255. PubMed 31493350 DOI 10.1002/cjp2.140

Resident memory CD8 T cells persist for years in human small intestine

Bartolomé-Casado R, Landsverk OJB, Chauhan SK, Richter L, Phung D, Greiff V, Risnes LF, Yao Y, Neumann RS, Yaqub S, Øyen O, Horneland R, Aandahl EM, Paulsen V, Sollid LM, Qiao SW, Baekkevold ES, Jahnsen FL (2019). Resident memory CD8 T cells persist for years in human small intestine. J Exp Med, 216 (10), 2412-2426. PubMed 31337737 DOI 10.1084/jem.20190414

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

Cassetta L, Baekkevold ES, Brandau S, Bujko A, Cassatella MA, Dorhoi A, Krieg C, Lin A, Loré K, Marini O, Pollard JW, Roussel M, Scapini P, Umansky V, Adema GJ (2019). Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates. Cancer Immunol Immunother, 68 (4), 687-697. PubMed 30684003 DOI 10.1007/s00262-019-02302-2

Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease

Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ (2018). Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease. Gastroenterology, 156 (5), 1428-1439.e10. PubMed 30593798 DOI 10.1053/j.gastro.2018.12.013